Distinct DNA methylation patterns characterize differentiated human embryonic stem cells and developing human fetal liver

To investigate the role of DNA methylation during human development, we developed Methyl-seq, a method that assays DNA methylation at more than 90,000 regions throughout the genome. Performing Methyl-seq on human embryonic stem cells (hESCs), their derivatives, and human tissues allowed us to identi...

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Detalhes bibliográficos
Main Authors: Brunner, Alayne L., Johnson, David S., Kim, Si Wan, Valouev, Anton, Reddy, Timothy E., Neff, Norma F., Anton, Elizabeth, Medina, Catherine, Nguyen, Loan, Chiao, Eric, Oyolu, Chuba B., Schroth, Gary P., Absher, Devin M., Baker, Julie C., Myers, Richard M.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2694474/
https://ncbi.nlm.nih.gov/pubmed/19273619
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.088773.108
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