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Cataracts Are Caused by Alterations of a Critical N-Terminal Positive Charge in Connexin50
PURPOSE: To elucidate the basis of the autosomal dominant congenital nuclear cataracts caused by the connexin50 mutant, CX50R23T, by determining its cellular distribution and functional behavior and the consequences of substituting other amino acids for arginine-23. METHODS: Connexin50 (CX50) mutant...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2694449/ https://ncbi.nlm.nih.gov/pubmed/18326694 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.07-1658 |
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