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De novo fatty-acid synthesis and related pathways as molecular targets for cancer therapy

Enhanced lipid biosynthesis is a characteristic feature of cancer. Deregulated lipogenesis plays an important role in tumour cell survival. These observations suggest that enzymes in the lipid synthesis pathway would be rational therapeutic targets for cancer. To this end, we review the enzymes in d...

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Bibliografske podrobnosti
Main Authors: Mashima, T, Seimiya, H, Tsuruo, T
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2009
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2694429/
https://ncbi.nlm.nih.gov/pubmed/19352381
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6605007
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