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De novo fatty-acid synthesis and related pathways as molecular targets for cancer therapy
Enhanced lipid biosynthesis is a characteristic feature of cancer. Deregulated lipogenesis plays an important role in tumour cell survival. These observations suggest that enzymes in the lipid synthesis pathway would be rational therapeutic targets for cancer. To this end, we review the enzymes in d...
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| Main Authors: | , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Nature Publishing Group
2009
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2694429/ https://ncbi.nlm.nih.gov/pubmed/19352381 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6605007 |
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