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Cost-effective HRMA pre-sequence typing of clone libraries; application to phage display selection

BACKGROUND: Methodologies like phage display selection, in vitro mutagenesis and the determination of allelic expression differences include steps where large numbers of clones need to be compared and characterised. In the current study we show that high-resolution melt curve analysis (HRMA) is a si...

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Détails bibliographiques
Auteurs principaux: Pepers, Barry A, Schut, Menno H, Vossen, Rolf HAM, van Ommen, Gert-Jan B, den Dunnen, Johan T, van Roon-Mom, Willeke MC
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2009
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2694173/
https://ncbi.nlm.nih.gov/pubmed/19463169
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1472-6750-9-50
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