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Regulation of androgen receptor transcriptional activity by rapamycin in prostate cancer cell proliferation and survival

The mTOR inhibitor rapamycin caused growth arrest in both androgen-dependent and androgen-independent prostate cancer cells; however, long-term treatment induced resistance to the drug. The goal of the present studies was to investigate methods that can overcome this resistance. Here we show that ra...

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Detalhes bibliográficos
Main Authors: Wang, Yu, Mikhailova, Margarita, Bose, Swagata, Pan, Chong-Xian, deVere White, Ralph W., Ghosh, Paramita M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2694040/
https://ncbi.nlm.nih.gov/pubmed/18776922
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2008.318
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