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Regulation of androgen receptor transcriptional activity by rapamycin in prostate cancer cell proliferation and survival
The mTOR inhibitor rapamycin caused growth arrest in both androgen-dependent and androgen-independent prostate cancer cells; however, long-term treatment induced resistance to the drug. The goal of the present studies was to investigate methods that can overcome this resistance. Here we show that ra...
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Main Authors: | , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2008
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2694040/ https://ncbi.nlm.nih.gov/pubmed/18776922 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2008.318 |
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