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The deazapurine biosynthetic pathway revealed: In vitro enzymatic synthesis of preQ(0) from guanosine-5′-triphosphate in four steps

Deazapurine-containing secondary metabolites comprise a broad range of structurally diverse nucleoside analogs found throughout biology including various antibiotics produced by species of Streptomyces bacteria and the hypermodified tRNA bases queuosine and archaeosine. Despite early interest in dea...

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Détails bibliographiques
Auteurs principaux: McCarty, Reid M., Somogyi, Árpád, Lin, Guangxin, Jacobsen, Neil E., Bandarian, Vahe
Format: Artigo
Langue:Inglês
Publié: 2009
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2693876/
https://ncbi.nlm.nih.gov/pubmed/19354300
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi900400e
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