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The deazapurine biosynthetic pathway revealed: In vitro enzymatic synthesis of preQ(0) from guanosine-5′-triphosphate in four steps

Deazapurine-containing secondary metabolites comprise a broad range of structurally diverse nucleoside analogs found throughout biology including various antibiotics produced by species of Streptomyces bacteria and the hypermodified tRNA bases queuosine and archaeosine. Despite early interest in dea...

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Detalhes bibliográficos
Main Authors: McCarty, Reid M., Somogyi, Árpád, Lin, Guangxin, Jacobsen, Neil E., Bandarian, Vahe
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2693876/
https://ncbi.nlm.nih.gov/pubmed/19354300
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi900400e
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