Cell Cycle Regulator Gene CDC5L, a Potential Target for 6p12-p21 Amplicon in Osteosarcoma

Osteosarcoma is a primary malignant tumor of bone arising from primitive bone-forming mesenchymal cells and accounts for ∼60% of malignant bone tumors. Our comparative genomic hybridization (CGH) studies have identified frequent amplification at 6p12-p21, 12q13-q15, and 17p11.2 in osteosarcoma. Of t...

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Detalhes bibliográficos
Main Authors: Lu, Xin-Yan, Lu, Yaojuan, Zhao, Yi-Jue, Jaeweon, Kim, Kang, Jason, Xiao-Nan, Li, Ge, Gouqing, Meyer, Rene, Perlaky, Laszlo, Hicks, John, Chintagumpala, Murali, Cai, Wei-Wen, Ladanyi, Marc, Gorlick, Richard, Lau, Ching C., Pati, Debananda, Sheldon, Michael, Rao, Pulivarthi H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2693718/
https://ncbi.nlm.nih.gov/pubmed/18567798
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1541-7786.MCR-07-2115
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