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Altered B cell receptor signaling in human systemic lupus erythematosus

Regulation of B cell receptor signaling is essential for the development of specific immunity while retaining tolerance to self. Systemic lupus erythematosus (SLE) is characterized by a loss of B cell tolerance and the production of anti-self antibodies. Accompanying this break down in tolerance are...

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Autors principals: Jenks, Scott A., Sanz, Iñaki
Format: Artigo
Idioma:Inglês
Publicat: 2008
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2693706/
https://ncbi.nlm.nih.gov/pubmed/18723129
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.autrev.2008.07.047
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