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Quantification of Isotopically Overlapping Deamidated and (18)O Labeled Peptides Using Isotopic Envelope Mixture Modeling

A robust peptide quantification method was developed where overlapping peptide isotopic distributions were fit with predicted peptide isotopic envelope mixture models (IEMM). Application to two difficult quantitative problems was demonstrated. The first was the quantification of deamidation, where m...

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מידע ביבליוגרפי
Main Authors: Dasari, Surendra, Wilmarth, Phillip A., Reddy, Ashok P., Robertson, Lucinda J. G., Nagalla, Srinivasa R., David, Larry L.
פורמט: Artigo
שפה:Inglês
יצא לאור: 2009
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC2693468/
https://ncbi.nlm.nih.gov/pubmed/19173613
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/pr801054w
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