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Quantification of Isotopically Overlapping Deamidated and (18)O Labeled Peptides Using Isotopic Envelope Mixture Modeling
A robust peptide quantification method was developed where overlapping peptide isotopic distributions were fit with predicted peptide isotopic envelope mixture models (IEMM). Application to two difficult quantitative problems was demonstrated. The first was the quantification of deamidation, where m...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2693468/ https://ncbi.nlm.nih.gov/pubmed/19173613 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/pr801054w |
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