BRCA1 Promoter Methylation is Associated with Increased Mortality among Women with Breast Cancer

Promoter-CpG island hypermethylation is a common molecular defect in cancer cells. It has been proposed as an alternative mechanism to inactivate BRCA1in the breast where somatic mutations of BRCA1 are rare. To better understand breast cancer etiology and progression, we explored the association bet...

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Autors principals: Xu, Xinran, Gammon, Marilie D., Zhang, Yujing, Bestor, Timothy H., Zeisel, Steven H., Wetmur, James G., Wallenstein, Sylvan, Bradshaw, Patrick T., Garbowski, Gail, Teitelbaum, Susan L., Neugut, Alfred I., Santella, Regina M., Chen, Jia
Format: Artigo
Idioma:Inglês
Publicat: 2008
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2693263/
https://ncbi.nlm.nih.gov/pubmed/18521744
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10549-008-0075-5
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