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Structural Basis for Polyproline Recognition by the FE65 WW Domain

The neuronal protein FE65 functions in brain development and Amyloid Precursor Protein (APP) signaling through its interaction with the mammalian enabled (Mena) protein and APP, respectively. The recognition of short polyproline sequences in Mena by the FE65 WW domain plays a central role in axon gu...

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Detalhes bibliográficos
Main Authors: Meiyappan, Muthuraman, Birrane, Gabriel, Ladias, John A.A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2693091/
https://ncbi.nlm.nih.gov/pubmed/17686488
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2007.06.064
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