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A Conformational Transition State Accompanies Tryptophan Activation by B. stearothermophilus Tryptophanyl-tRNA Synthetase

B. stearothermophilus tryptophanyl-tRNA synthetase catalysis proceeds via high-energy protein conformations. Unliganded MD trajectories of the Pre-Transition-state complex with Mg(2+)•ATP and the (post) transition-state analog complex with adenosine tetraphosphate relax rapidly in opposite direction...

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Detaylı Bibliyografya
Asıl Yazarlar: Kapustina, Maryna, Weinreb, Violetta, Li, Li, Kuhlman, Brian, Carter, Charles W.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2007
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2693061/
https://ncbi.nlm.nih.gov/pubmed/17937916
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2007.08.010
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