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Evidence for an Interaction between the SH3 Domain and the N-terminal Extension of the Essential Light Chain in Class II Myosins

The function of the src-homology 3 (SH3) domain in class II myosins, a distinct β-barrel structure, remains unknown. Here we provide evidence, using electron cryomicroscopy, in conjunction with light scattering, fluorescence and kinetic analyses, that the SH3 domain facilitates the binding of the N-...

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Detalhes bibliográficos
Main Authors: Lowey, Susan, Saraswat, Lakshmi D., Liu, HongJun, Volkmann, Niels, Hanein, Dorit
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2693010/
https://ncbi.nlm.nih.gov/pubmed/17597155
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2007.05.080
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