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Binding of intrinsically disordered proteins is not necessarily accompanied by a structural transition to a folded form

There are a large number of protein domains and even entire proteins, lacking ordered structure under physiological conditions. Intriguingly, a highly flexible, random coil-like conformation is the native and functional state for many proteins known to be involved in cell signaling. An example is a...

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Detaylı Bibliyografya
Asıl Yazarlar: Sigalov, Alexander B., Zhuravleva, Anastasia V., Orekhov, Vladislav Yu.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2006
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2692994/
https://ncbi.nlm.nih.gov/pubmed/17174464
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biochi.2006.11.003
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