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Binding of intrinsically disordered proteins is not necessarily accompanied by a structural transition to a folded form
There are a large number of protein domains and even entire proteins, lacking ordered structure under physiological conditions. Intriguingly, a highly flexible, random coil-like conformation is the native and functional state for many proteins known to be involved in cell signaling. An example is a...
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| Asıl Yazarlar: | , , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
2006
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2692994/ https://ncbi.nlm.nih.gov/pubmed/17174464 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biochi.2006.11.003 |
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