The combination effect of sodium butyrate and 5-Aza-2'-deoxycytidine on radiosensitivity in RKO colorectal cancer and MCF-7 breast cancer cell lines

BACKGROUND: The overall level of chromatin compaction is an important mechanism of radiosensitivity, and modification of DNA methylation and histone deacetylation may increase radiosensitivity by altering chromatin compaction. In this study, we investigated the effect of a demethylating agent, a his...

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Hoofdauteurs: Cho, Hang Joo, Kim, Sin Young, Kim, Kee Hwan, Kang, Won Kyung, kim, Ji Il, Oh, Seong Tack, Kim, Jeong Soo, An, Chang Hyeok
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: BioMed Central 2009
Onderwerpen:
Research
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2692973/
https://ncbi.nlm.nih.gov/pubmed/19460134
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1477-7819-7-49
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