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A Versatile Cyclodehydration Reaction for the Synthesis of Isoquinoline and β-Carboline Derivatives
[Image: see text] The direct conversion of various amides to isoquinoline and β-carboline derivatives via mild electrophilic amide activation, with trifluoromethanesulfonic anhydride in the presence of 2-chloropyridine, is described. Low temperature amide activation followed by cyclodehydration upon...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2692836/ https://ncbi.nlm.nih.gov/pubmed/18642832 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol801264u |
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