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Bone Marrow Stromal Cell Therapy Reduces proNGF and p75 Expression in Mice with Experimental Autoimmune Encephalomyelitis
Demyelination is prominent in experimental autoimmune encephalomyelitis (EAE). The receptor p75 and its high affinity ligand proNGF are required for oligodendrocyte death after injury. We hypothesize that bone marrow stromal cells (BMSCs) provide therapeutic benefit in EAE mice by reducing proNGF/p7...
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| Autori principali: | , , , , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2009
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2692832/ https://ncbi.nlm.nih.gov/pubmed/19193386 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jns.2008.12.033 |
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