The Resistance of Electron Transport Chain Fe-S Clusters to Oxidative Damage during the Reaction of Peroxynitrite with Mitochondrial Complex II and Rat Heart Pericardium

The effects of peroxynitrite and nitric oxide on the iron-sulfur clusters in complex II (succinate dehydrogenase) isolated from bovine heart have been studied primarily by EPR spectroscopy and no measurable damage to the constitutive 2Fe-2S, 3Fe-4S, or 4Fe-4S clusters was observed. The enzyme can be...

Full description

Saved in:
Bibliographic Details
Main Authors: Pearce, Linda L., Martinez-Bosch, Sandra, Manzano, Elisenda Lopez, Winnica, Daniel E., Epperly, Michael W., Peterson, Jim
Format: Artigo
Language:Inglês
Published: 2008
Subjects:
Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2692736/
https://ncbi.nlm.nih.gov/pubmed/19118636
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.niox.2008.12.001
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items