The Resistance of Electron Transport Chain Fe-S Clusters to Oxidative Damage during the Reaction of Peroxynitrite with Mitochondrial Complex II and Rat Heart Pericardium

The effects of peroxynitrite and nitric oxide on the iron-sulfur clusters in complex II (succinate dehydrogenase) isolated from bovine heart have been studied primarily by EPR spectroscopy and no measurable damage to the constitutive 2Fe-2S, 3Fe-4S, or 4Fe-4S clusters was observed. The enzyme can be...

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Autores principales: Pearce, Linda L., Martinez-Bosch, Sandra, Manzano, Elisenda Lopez, Winnica, Daniel E., Epperly, Michael W., Peterson, Jim
Formato: Artigo
Lenguaje:Inglês
Publicado: 2008
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2692736/
https://ncbi.nlm.nih.gov/pubmed/19118636
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.niox.2008.12.001
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