Crystal Structure of Bacillus stearothermophilus UvrA Provides Insight into ATP-modulated Dimerization, UvrB Interaction and DNA Binding

The nucleotide excision repair pathway corrects many structurally unrelated DNA lesions. Damage recognition in bacteria is performed by UvrA, a member of the ABC ATPase superfamily whose functional form is a dimer with four nucleotide-binding domains (NBD), two per protomer. In the 3.2-Å structure o...

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Main Authors: Pakotiprapha, Danaya, Inuzuka, Yoshihiko, Bowman, Brian R., Moolenaar, Geri F., Goosen, Nora, Jeruzalmi, David, Verdine, Gregory L.
Formato: Artigo
Idioma:Inglês
Publicado: 2007
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2692698/
https://ncbi.nlm.nih.gov/pubmed/18158267
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2007.10.026
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