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Single-molecule analysis reveals two separate DNA-binding domains in the Escherichia coli UvrA dimer

The UvrA protein is the initial damage-recognizing factor in bacterial nucleotide excision repair. Each monomer of the UvrA dimer contains two ATPase sites. Using single-molecule analysis we show that dimerization of UvrA in the presence of ATP is significantly higher than with ADP or nonhydrolyzabl...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Wagner, Koen, Moolenaar, Geri, van Noort, John, Goosen, Nora
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Oxford University Press 2009
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2665241/
https://ncbi.nlm.nih.gov/pubmed/19208636
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkp071
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