Ha-Ras transformation of MCF10A cells leads to repression of Singleminded-2s through NOTCH and C/EBPβ

We have previously shown that Singleminded-2s (SIM2s), a member of the basic helix-loop-helix Per-Arnt-Sim (bHLH/PAS) family of transcription factors, is downregulated in breast cancer samples and has tumor suppressor activity. However, the mechanism by which SIM2s is repressed in breast cancer cell...

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Hlavní autoři: Gustafson, TL, Wellberg, E, Laffin, B, Schilling, L, Metz, RP, Zahnow, CA, Porter, WW
Médium: Artigo
Jazyk:Inglês
Vydáno: 2009
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2692552/
https://ncbi.nlm.nih.gov/pubmed/19169276
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2008.497
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