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Using Ion Channel-Forming Peptides to Quantify Protein-Ligand Interactions

This paper proposes a method for sensing affinity interactions by triggering disruption of self-assembly of ion channel-forming peptides in planar lipid bilayers. It shows that the binding of a derivative of alamethicin carrying a covalently attached sulfonamide ligand to carbonic anhydrase II (CA I...

詳細記述

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書誌詳細
主要な著者: Mayer, Michael, Semetey, Vincent, Gitlin, Irina, Yang, Jerry, Whitesides, George M.
フォーマット: Artigo
言語:Inglês
出版事項: 2008
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2692494/
https://ncbi.nlm.nih.gov/pubmed/18179217
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja077555f
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