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Using Ion Channel-Forming Peptides to Quantify Protein-Ligand Interactions
This paper proposes a method for sensing affinity interactions by triggering disruption of self-assembly of ion channel-forming peptides in planar lipid bilayers. It shows that the binding of a derivative of alamethicin carrying a covalently attached sulfonamide ligand to carbonic anhydrase II (CA I...
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| Hlavní autoři: | , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2008
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2692494/ https://ncbi.nlm.nih.gov/pubmed/18179217 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja077555f |
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