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MyoGEF regulates the invasion activity of MDA-MB-231 breast cancer cells through activation of RhoA and RhoC

The small GTPase proteins RhoA and RhoC are essential for tumor invasion and/or metastasis in breast carcinomas. However, it is poorly understood how RhoA and RhoC are activated in breast cancer cells. Here we describe the role of MyoGEF in regulating RhoA and RhoC activation as well as cell polarit...

詳細記述

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書誌詳細
主要な著者: Wu, Di, Asiedu, Michael, Wei, Qize
フォーマット: Artigo
言語:Inglês
出版事項: 2009
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2692373/
https://ncbi.nlm.nih.gov/pubmed/19421144
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2009.96
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