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Convergence of multiple signaling pathways is required to coordinately up-regulate mtDNA and mitochondrial biogenesis during T cell activation

The quantity and activity of mitochondria vary dramatically in tissues and are modulated in response to changing cellular energy demands and environmental factors. The amount of mitochondrial DNA (mtDNA), which encodes essential subunits of the oxidative phosphorylation complexes required for cellul...

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Detalhes bibliográficos
Main Authors: D’Souza, Anthony D., Parikh, Neal, Kaech, Susan M., Shadel, Gerald S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2692272/
https://ncbi.nlm.nih.gov/pubmed/17890163
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mito.2007.08.001
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