Structural and functional bases for broad-spectrum neutralization of avian and human influenza A viruses

Influenza virus remains a serious health threat, owing to its ability to evade immune surveillance through rapid genetic drift and reassortment. Here we used a human non-immune antibody phage-display library and the H5 hemagglutinin ectodomain to select ten neutralizing antibodies (nAbs) that were e...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Sui, Jianhua, Hwang, William C, Perez, Sandra, Wei, Ge, Aird, Daniel, Chen, Li-mei, Santelli, Eugenio, Stec, Boguslaw, Cadwell, Greg, Ali, Maryam, Wan, Hongquan, Murakami, Akikazu, Yammanuru, Anuradha, Han, Thomas, Cox, Nancy J, Bankston, Laurie A, Donis, Ruben O, Liddington, Robert C, Marasco, Wayne A
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group US 2009
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2692245/
https://ncbi.nlm.nih.gov/pubmed/19234466
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.1566
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