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Can Morphing Methods Predict Intermediate Structures?

Movement is crucial to the biological function of many proteins, yet crystallographic structures of proteins can give us only a static snapshot. The protein dynamics that are important to biological function often happen on a timescale that is unattainable through detailed simulation methods such as...

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Bibliographic Details
Main Authors: Weiss, Dahlia R., Levitt, Michael
Format: Artigo
Language:Inglês
Published: 2008
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2691871/
https://ncbi.nlm.nih.gov/pubmed/18996395
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2008.10.064
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