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Interleukin 21 up-regulates perforin-mediated cytotoxic activity of human intra-epithelial lymphocytes
Human intra-epithelial lymphocytes (IELs) are predominantly T-cell receptor-αβ(+) (TCR-αβ(+)) CD8(+) CD45RO(+) memory T cells located between intestinal epithelial cells. They respond to a greater extent to stimulation with interleukin (IL)-15 than to CD3/TCR triggering, suggesting that they react t...
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Blackwell Science Inc
2009
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| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2691786/ https://ncbi.nlm.nih.gov/pubmed/19489126 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2567.2008.02941.x |
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