MIF homologues from a filarial nematode parasite synergize with IL-4 to induce alternative activation of host macrophages

Macrophage migration inhibitory factor (MIF) is a highly conserved cytokine considered to exert wide-ranging, proinflammatory effects on the immune system. Recently, members of this gene family have been discovered in a number of invertebrate species, including parasitic helminths. However, chronic...

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Bibliographic Details
Main Authors: Prieto-Lafuente, Lidia, Gregory, William F., Allen, Judith E., Maizels, Rick M.
Format: Artigo
Language:Inglês
Published: The Society for Leukocyte Biology 2009
Subjects:
Inflammation, Extracellular Mediators, and Effector Molecules
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2691607/
https://ncbi.nlm.nih.gov/pubmed/19179453
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1189/jlb.0808459
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