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Thermodynamics of Multivalent Carbohydrate-Lectin Cross-linking Interactions: Importance of Entropy in the Bind and Jump Mechanism

The high affinity (Kd = 0.2 nM) of the soybean agglutinin (SBA), a tetrameric GalNAc specific lectin, for a modified form of porcine submaxillary mucin, a linear glycoprotein, that possessing a molecular mass of ~10(6) daltons and ~2300 GalNAcα1-O-Ser/-Thr residues (Tn-PSM) has been ascribed to an i...

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Detaylı Bibliyografya
Asıl Yazarlar: Dam, Tarun K., Gerken, Thomas A., Brewer, C. Fred
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2009
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2691598/
https://ncbi.nlm.nih.gov/pubmed/19292456
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi9002919
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