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Thermodynamics of Multivalent Carbohydrate-Lectin Cross-linking Interactions: Importance of Entropy in the Bind and Jump Mechanism
The high affinity (Kd = 0.2 nM) of the soybean agglutinin (SBA), a tetrameric GalNAc specific lectin, for a modified form of porcine submaxillary mucin, a linear glycoprotein, that possessing a molecular mass of ~10(6) daltons and ~2300 GalNAcα1-O-Ser/-Thr residues (Tn-PSM) has been ascribed to an i...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2691598/ https://ncbi.nlm.nih.gov/pubmed/19292456 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi9002919 |
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