Production of Infectious Genotype 1b Virus Particles in Cell Culture and Impairment by Replication Enhancing Mutations

With the advent of subgenomic hepatitis C virus (HCV) replicons, studies of the intracellular steps of the viral replication cycle became possible. These RNAs are capable of self-amplification in cultured human hepatoma cells, but save for the genotype 2a isolate JFH-1, efficient replication of thes...

Description complète

Enregistré dans:
Détails bibliographiques
Auteurs principaux: Pietschmann, Thomas, Zayas, Margarita, Meuleman, Philip, Long, Gang, Appel, Nicole, Koutsoudakis, George, Kallis, Stephanie, Leroux-Roels, Geert, Lohmann, Volker, Bartenschlager, Ralf
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2009
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2691593/
https://ncbi.nlm.nih.gov/pubmed/19521536
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1000475
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires