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Efficient trans-Encapsidation of Hepatitis C Virus RNAs into Infectious Virus-Like Particles

Recently, complete replication of hepatitis C virus (HCV) in tissue culture was established using the JFH1 isolate. To analyze determinants of HCV genome packaging and virion assembly, we developed a system that supports particle production based on trans-packaging of subgenomic viral RNAs. Using JF...

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Detalhes bibliográficos
Main Authors: Steinmann, Eike, Brohm, Christiane, Kallis, Stephanie, Bartenschlager, Ralf, Pietschmann, Thomas
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2446957/
https://ncbi.nlm.nih.gov/pubmed/18480457
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00118-08
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