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Role of Physiological Intestinal Water in Oral Absorption
Water volume has impact when the compound has low aqueous solubility. For example, the absorption of compounds with a Biopharmaceutics Classification System class 2 or 4 is likely to be solubility-limited. Provided the formulation does not contribute to a dissolution-limited condition (e.g., particl...
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| Main Author: | |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
Springer US
2009
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| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2691455/ https://ncbi.nlm.nih.gov/pubmed/19412669 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12248-009-9087-2 |
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