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Role of Physiological Intestinal Water in Oral Absorption

Water volume has impact when the compound has low aqueous solubility. For example, the absorption of compounds with a Biopharmaceutics Classification System class 2 or 4 is likely to be solubility-limited. Provided the formulation does not contribute to a dissolution-limited condition (e.g., particl...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijä: Sutton, Steven C.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Springer US 2009
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2691455/
https://ncbi.nlm.nih.gov/pubmed/19412669
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12248-009-9087-2
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