Functional recombinant MHC class II molecules and high-throughput peptide-binding assays

BACKGROUND: Molecules of the class II major histocompability complex (MHC-II) specifically bind and present exogenously derived peptide epitopes to CD4+ T helper cells. The extreme polymorphism of the MHC-II hampers the complete analysis of peptide binding. It is also a significant hurdle in the gen...

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Main Authors: Justesen, Sune, Harndahl, Mikkel, Lamberth, Kasper, Nielsen, Lise-Lotte B, Buus, Søren
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2009
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2690590/
https://ncbi.nlm.nih.gov/pubmed/19416502
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1745-7580-5-2
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