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The paracaspase MALT1 controls caspase-8 activation during lymphocyte proliferation
Caspase-8, an initiator caspase involved in lymphocyte apoptosis, is paradoxically required for lymphocyte proliferation. It is not understood how caspase-8 is controlled during antigenic signaling to allow for activation while averting triggering apoptosis. Here we show that caspase-8 undergoes lim...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2008
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2690087/ https://ncbi.nlm.nih.gov/pubmed/18691973 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2008.06.008 |
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