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LKB1 regulates polarity remodeling and adherens junction formation in the Drosophila eye

The serine–threonine kinase LKB1 regulates cell polarity from Caenorhabditis elegans to man. Loss of lkb1 leads to a cancer predisposition, known as Peutz–Jeghers Syndrome. Biochemical analysis indicates that LKB1 can phosphorylate and activate a family of AMPK- like kinases, however, the precise co...

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Bibliografiska uppgifter
Huvudupphovsmän: Amin, Nancy, Khan, Afifa, St. Johnston, Daniel, Tomlinson, Ian, Martin, Sophie, Brenman, Jay, McNeill, Helen
Materialtyp: Artigo
Språk:Inglês
Publicerad: National Academy of Sciences 2009
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2690039/
https://ncbi.nlm.nih.gov/pubmed/19443685
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0812469106
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