Genetic Variation of Promoter Sequence Modulates XBP1 Expression and Genetic Risk for Vitiligo

Our previous genome-wide linkage analysis identified a susceptibility locus for generalized vitiligo on 22q12. To search for susceptibility genes within the locus, we investigated a biological candidate gene, X-box binding protein 1(XBP1). First, we sequenced all the exons, exon-intron boundaries as...

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Bibliographische Detailangaben
Hauptverfasser: Ren, Yunqing, Yang, Sen, Xu, Shengxin, Gao, Min, Huang, Wei, Gao, Tianwen, Fang, Qiaoyun, Quan, Cheng, Zhang, Chi, Sun, Liangdan, Liang, Yanhua, Han, Jianwen, Wang, Zhimin, Zhang, Fengyu, Zhou, Youwen, Liu, Jianjun, Zhang, Xuejun
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2009
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2689933/
https://ncbi.nlm.nih.gov/pubmed/19543371
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1000523
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