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Genetic polymorphism of the Nrf2 promoter region is associated with vitiligo risk in Han Chinese populations

The nuclear factor erythroid‐derived two‐like 2‐antioxidant response element (Nrf2‐ARE) pathway and its downstream antioxidant enzyme heme oxygenase‐1 (HMOX1 or HO‐1) play essential roles in H(2)O(2)‐induced oxidative damage in human melanocytes. However, the link between Nrf2 promoter polymorphisms...

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Publicado en:J Cell Mol Med
Autores principales: Song, Pu, Li, Kai, Liu, Ling, Wang, Xiaowen, Jian, Zhe, Zhang, Weigang, Wang, Gang, Li, Chunying, Gao, Tianwen
Formato: Artigo
Lenguaje:Inglês
Publicado: John Wiley and Sons Inc. 2016
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5020638/
https://ncbi.nlm.nih.gov/pubmed/27222475
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.12874
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