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Nonenzymatic displacement of chlorine and formation of free radicals upon the reaction of glutathione with PCB quinones

The reactions of glutathione (GSH) with polychlorinated biphenyl (PCB) quinones having different degrees of chlorination on the quinone ring were examined. EPR spectroscopy and MS revealed 2 types of reactions yielding different products: (i) a nonenzymatic, nucleophilic displacement of chlorine on...

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Detalhes bibliográficos
Main Authors: Song, Yang, Wagner, Brett A., Witmer, Jordan R., Lehmler, Hans-Joachim, Buettner, Garry R.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2689812/
https://ncbi.nlm.nih.gov/pubmed/19497881
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0810352106
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