Stable Isotope Labeling by Amino Acids in Cell Culture (SILAC) and Quantitative Comparison of the Membrane Proteomes of Self-renewing and Differentiating Human Embryonic Stem Cells

Stable isotope labeling by amino acids in cell culture (SILAC) is a powerful quantitative proteomics platform for comprehensive characterization of complex biological systems. However, the potential of SILAC-based approaches has not been fully utilized in human embryonic stem cell (hESC) research ma...

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Main Authors: Prokhorova, Tatyana A., Rigbolt, Kristoffer T. G., Johansen, Pia T., Henningsen, Jeanette, Kratchmarova, Irina, Kassem, Moustapha, Blagoev, Blagoy
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2009
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2689770/
https://ncbi.nlm.nih.gov/pubmed/19151416
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.M800287-MCP200
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