Phosphoproteomic profiling reveals a defined genetic program for osteoblastic lineage commitment of human bone marrow–derived stromal stem cells

Bone marrow–derived mesenchymal stem cells (MSCs) differentiate into osteoblasts upon stimulation by signals present in their niche. Because the global signaling cascades involved in the early phases of MSCs osteoblast (OB) differentiation are not well-defined, we used quantitative mass spectrometry...

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Gepubliceerd in:Genome Res
Hoofdauteurs: Barrio-Hernandez, Inigo, Jafari, Abbas, Rigbolt, Kristoffer T.G., Hallenborg, Philip, Sanchez-Quiles, Virginia, Skovrind, Ida, Akimov, Vyacheslav, Kratchmarova, Irina, Dengjel, Joern, Kassem, Moustapha, Blagoev, Blagoy
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Cold Spring Harbor Laboratory Press 2020
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6961576/
https://ncbi.nlm.nih.gov/pubmed/31831592
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.248286.119
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