Phosphoproteomic profiling reveals a defined genetic program for osteoblastic lineage commitment of human bone marrow–derived stromal stem cells

Bone marrow–derived mesenchymal stem cells (MSCs) differentiate into osteoblasts upon stimulation by signals present in their niche. Because the global signaling cascades involved in the early phases of MSCs osteoblast (OB) differentiation are not well-defined, we used quantitative mass spectrometry...

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Pubblicato in:Genome Res
Autori principali: Barrio-Hernandez, Inigo, Jafari, Abbas, Rigbolt, Kristoffer T.G., Hallenborg, Philip, Sanchez-Quiles, Virginia, Skovrind, Ida, Akimov, Vyacheslav, Kratchmarova, Irina, Dengjel, Joern, Kassem, Moustapha, Blagoev, Blagoy
Natura: Artigo
Lingua:Inglês
Pubblicazione: Cold Spring Harbor Laboratory Press 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6961576/
https://ncbi.nlm.nih.gov/pubmed/31831592
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.248286.119
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