Selectivity in Enrichment of cAMP-dependent Protein Kinase Regulatory Subunits Type I and Type II and Their Interactors Using Modified cAMP Affinity Resins

cAMP regulates cellular functions primarily by activating PKA. The involvement of PKAs in various signaling pathways occurring simultaneously in different cellular compartments necessitates stringent spatial and temporal regulation. This specificity is largely achieved by binding of PKA to protein s...

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Autors principals: Aye, Thin Thin, Mohammed, Shabaz, van den Toorn, Henk W. P., van Veen, Toon A. B., van der Heyden, Marcel A. G., Scholten, Arjen, Heck, Albert J. R.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2009
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2689760/
https://ncbi.nlm.nih.gov/pubmed/19119138
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.M800226-MCP200
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