Selectivity in Enrichment of cAMP-dependent Protein Kinase Regulatory Subunits Type I and Type II and Their Interactors Using Modified cAMP Affinity Resins

cAMP regulates cellular functions primarily by activating PKA. The involvement of PKAs in various signaling pathways occurring simultaneously in different cellular compartments necessitates stringent spatial and temporal regulation. This specificity is largely achieved by binding of PKA to protein s...

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Main Authors: Aye, Thin Thin, Mohammed, Shabaz, van den Toorn, Henk W. P., van Veen, Toon A. B., van der Heyden, Marcel A. G., Scholten, Arjen, Heck, Albert J. R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2009
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2689760/
https://ncbi.nlm.nih.gov/pubmed/19119138
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.M800226-MCP200
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