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Interferon γ is recognised by importin α/β: Enhanced nuclear localising and transactivation activities of an interferon γ mimetic

Interferon (IFN) γ's ability to localise in the nucleus and function in gene activation has been known for some time, although the role of the conventional nuclear transporting importin molecules is unclear. Here, we demonstrate for the first time the direct recognition of IFNγ and an IFNγ mime...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Fulcher, Alex J., Ahmed, Chulbul M.I., Noon-Song, Ezra N., Kwan, Rain Y.Q., Subramaniam, Prem S., Johnson, Howard M., Jans, David A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2008
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2689648/
https://ncbi.nlm.nih.gov/pubmed/18405666
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.febslet.2008.03.054
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