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Interferon γ is recognised by importin α/β: Enhanced nuclear localising and transactivation activities of an interferon γ mimetic

Interferon (IFN) γ's ability to localise in the nucleus and function in gene activation has been known for some time, although the role of the conventional nuclear transporting importin molecules is unclear. Here, we demonstrate for the first time the direct recognition of IFNγ and an IFNγ mime...

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Detalhes bibliográficos
Main Authors: Fulcher, Alex J., Ahmed, Chulbul M.I., Noon-Song, Ezra N., Kwan, Rain Y.Q., Subramaniam, Prem S., Johnson, Howard M., Jans, David A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2689648/
https://ncbi.nlm.nih.gov/pubmed/18405666
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.febslet.2008.03.054
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