Frequent mutations of the CA simple sequence repeat in intron 1 of EGFR in mismatch repair-deficient colorectal cancers

AIM: To investigate the polymorphic simple sequence repeat in intron 1 of the epidermal growth factor receptor gene (EGFR) (CA-SSRI), which is known to affect the efficiency of gene transcription as a putative target of the mismatch repair (MMR) machinery in colorectal tumors. METHODS: The CA-SSR I...

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Autors principals: Buisine, Marie-Pierre, Wacrenier, Agnès, Mariette, Christophe, Leteurtre, Emmanuelle, Escande, Fabienne, Aissi, Sana, Ketele, Amandine, Leclercq, Annette, Porchet, Nicole, Lesuffleur, Thécla
Format: Artigo
Idioma:Inglês
Publicat: The WJG Press and Baishideng 2008
Matèries:
Colorectal Cancer
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2689408/
https://ncbi.nlm.nih.gov/pubmed/18286687
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.14.1053
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