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Reconstruction of Escherichia coli transcriptional regulatory networks via regulon-based associations

BACKGROUND: Network reconstruction methods that rely on covariance of expression of transcription regulators and their targets ignore the fact that transcription of regulators and their targets can be controlled differently and/or independently. Such oversight would result in many erroneous predicti...

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Autori principali: Zare, Hossein, Sangurdekar, Dipen, Srivastava, Poonam, Kaveh, Mostafa, Khodursky, Arkady
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2689187/
https://ncbi.nlm.nih.gov/pubmed/19366454
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1752-0509-3-39
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